Astragalus Membranaceus Root Extract Astragaloside Produced by Herbal Factory Pincredit
The main active ingredients of astragalus membranaceus root extract are the Astragaloside IV , Astragalus Polysaccharides and Astragalus membranaceus Glucoside, derived from the dry roots of Astragalus membranaceus or Astragalus membranaceus, also some can be from astragalus root powder.. Chinese Pharmacopoeia showed that the main efficacy of astragalus membranaceus root extract was: Health food and medicine.
Based on local material bulk,We Xian Pincredit is professional for the prodcution of astragalus membranaceus root extract.main specification is (20-50%), astragaloside IV (0.1% -10%) and myrone isoflavone glucoside (Pseudomonas aeruginosa), We cooperated with some domestic pharmaceutical enterprises and supply the astragalus membranaceus root extract stable , in particular, especially the Astragaloside IV 10% has been supplied to many medicine manufacturer who are from United States, Canada, Poland.
The astragalus membranaceus root extract specifications
Product Name: astragalus membranaceus root extract;
Source: Membrane Pods Astragalus root or Astragalus root powder;
Specification:Astragaloside IV (0.01% -10%) (HPLC); Astragalus polysaccharides: 20-50% (UV);
Packing: 1-5KG with aluminum foil bag package; the whole 10 or 25KG cardboard drum package;
Production process: the astragalus membranaceus root extract from the legume plant pods Astragalus root, clean and dried; some crushed into 10-20 mesh astragalus root powder, add solvent in 80 ℃ extraction three times ;And the filtrate was concentrated at 70 ° C under reduced pressure to a clear paste having a relative density of 1.18 to 1.22 . spray drying finally, the astragalus polysaccharide was finished,the high content of astragaloside IV can be further purified and refined.
Physical and chemical indexes of astragalus membranaceus root extract
Loss on drying ≤ 5.00%
Ignition residue ≤ 5.00%
Lead ≤ 0.5 (Pb, mg / kg)
Cadmium ≤ 0.3 (in terms of Cd, mg / kg)
Arsenic ≤ 0.3 (in As, mg / kg)
Mercury ≤ 0.2 (in Hg, mg / kg)
The total number of colonies ≤ 3000 (cfu / g)
Escherichia coli ≤ 40 (MPN / 100g)
Mold ≤ 100 (cfu / g)
Yeast ≤ 100 (cfu / g)
Test of Astragaloside Ⅳ
According to high performance liquid chromatography (General 0512).
Chromatographic conditions and system suitability test with octadecyl silane bonded silica as a filler; acetonitrile - water (32:68) as the mobile phase; evaporative light scattering detector detection. Theoretical plate number according to Astragaloside IV peak should not be less than 4000.
Preparation of the reference solution to take Astragaloside reference substance amount, accurately weighed, plus methanol made per 1ml containing 0.5mg solution, that is, too.
Preparation of the test solution to take Astragaloside powder about 4g, accurately weighed, set Soxhlet extractor, add methanol 40ml, cold soaked overnight, plus the amount of methanol, heating reflux 4 hours, the extract recovery solvent and concentrated To dry, the residue of water 10ml, slightly heat to dissolve, saturated with water saturated n-butanol shaking extraction 4 times, each 40ml, combined with n-butanol solution, with ammonia test solution to wash twice, each 40ml, abandoned ammonia Liquid, n-butanol liquid evaporated, the residue of water 5ml to dissolve, let cool, through the D101-type macroporous adsorption resin column (diameter 1.5cm, column height of 12cm), 50ml water elution, discard the water, and then With 40% ethanol 30ml elution, discard the eluent, followed by 70% ethanol 80ml elution, collecting eluent, evaporated, the residue dissolved in methanol, transferred to 5ml volumetric flask, add methanol to the mark, shake ,Okay.
Weighing the reference solution and test solution both 10μl, into the liquid chromatograph, with the external standard two-point logarithmic equation calculation, got the data of astragaloside IV.